Reported Deaths tool of influenza and pneumonia of 10th week (March 03/March 09) is 926. Total reported deaths of influenza and pneumonia from August 26, 2012 to March 09, 2013 in the United States is 22'823.

United States's Influenza Activities of 10 th week *March 03 / March 09 of 2013

Reported Deaths tool of influenza and pneumonia of 10th week (March 03/March 09) is 926. Total reported deaths of influenza and pneumonia from August 26, 2012 to March 09, 2013 in the United States  is 22'823.


アメリカ合州国の2013年第10週03/03ー03/09の肺炎·インフルエンザ(風邪)感染死者は、0926人。アメリカ合衆国の2012年第35週の08/26から, 2013年第10週の03/09までの122大都市のインフルエンザ(風邪)·肺炎の感染死者報告総数は、2万2823人

2013年03月15日金曜日発表
警告! インフルエンザの電網冊子(WEB SITE)には、あなたの電脳機をヴィールス伝染するところがおおいので、アンチヴィールスのソフトを導入したほうがよい。書き込みの妨害や、操作停止や、アクセス不能になる時がある。WINDOWS XPでは、WINDOWS UPDATE, windows defenderを 導入するとよい。
無料のアンチビールスでは、AVG FREE ー ANTIVIRUS DOWNROAD / FREE VIRUS PROTECTION http://www.avg.com
PROGRAMA ANTIVIRUS GRATIS / ANTIVIRUS Y ANTISPYWARE GRATIS / AVG FREE
free.avg.com/es-es/antivirus-grats-avg(スペイン語のソフト?)

avast, Download Free Antivirus Software on Intenet Security

http://www.avast.com

*********************************************************************

US -- Centers for Disease Contrl and Prevention (CDC)
> http://www.cdc.gov/
Publications
> Morbidity and Mortality Weekl Report (MMWR)
MMWR Home
Publications
> Weekly Repot
MMWR Weekly : Current Volume (2012)
March 15, 2013 / Vol. 62 / no. 1 0
> · Notifible Diseases and Mortality Tables

> . Table I, Provisional cases of infrequently reported notifiable diseases ( < 1'000 cases reported during the recently year ) United States, week ending (March 02-) March 09, 2013 (10th Week)

+ Influenza - associated pediatric mortality

Decembr 23-December 29, 2012(52th week) 02,/ acumulated 2012; 52,/ 2011 total; 118,/ 2010 total; 61,/ 2009 total; 358,/ 2008 total; 90,/ 2007 total; 77

> Table III Deaths in 122 U.S. cities, week ending (March 03-) March 09, 2013 (10th Week)
Pneumonia and influenza total daeths are 0926.

アメリカ合州国の2010年/2011年の風邪流行季節の122都市の肺炎·風邪インフルエンザ感染死者数
2010/第35週08/29ー09/04の肺炎·風邪感染死者は、609人。
2010/第36週09/05ー09/11の肺炎·風邪感染死者は、572人。
2010/第37週09/12ー09/18の肺炎·風邪感染死者は、759人。
2010/第38週の09/19ー09/25の肺炎·風邪感 染死者は、674人。
2010/第39週の09/26ー10/02の肺炎·風邪感染死者は、634人。
2010/第40週10/03ー10/09の肺炎·風邪感染死者は, 700人
2010/第41週10/10ー10/16の肺炎·風邪感染死者は、663人。
2010/第42週10/17ー10/23の肺炎·風邪感染死者は、726人。
2010/第43週10/24ー10/30の肺炎·風邪感染死者は、720人。
2010/第44週の10/31ー11/06の肺炎·風邪感 染死者は、736人。
2010/第45週の11/07ー11/13の肺炎·風邪感染死者は、723人。
2010/第46週の11/14ー11/20の肺炎·風邪感染死者は、731人。
2010/第47週の11/21ー11/27の肺炎·風邪感染死者は、516人。
2010/第48週11/28ー12/04の肺炎·風邪感染死者は、796人。
2010/第49週12/05ー12/11の肺炎·風邪感染死者は851人
2010/第50週12/12ー12/19の肺炎·風邪感染死者は、801人。
2010/第51週12/20ー12/26の肺炎·風邪感染死者は、705人。
2010/第52週12/27ー2011/01/02の感染死者は、657人。

2011/第01週の01/02ー01/08の肺炎·風邪感 染死者は、1025人。
2011/第02週の01/09ー01/15の肺炎·風邪感染死者は、 915人。
2011/第03週の01/16ー01/22の肺炎·風邪感 染死者は、 911人。
2011/第04週の01/23ー01/29の肺炎·風邪感染死者は、 983人。
2011/第05週の01/30ー02/05の肺炎·風邪感 染死者は、 934人。
2011/第06週の02/06ー02/12の肺炎·風邪感染死者は、 1080人
2011/第07週の02/13ー02/19の肺炎·風邪感 染死者は、1012人。
2011/第08週の02/20ー02/26の肺炎·風邪感染死者は、 0989人。
2011/第09週の02/27ー03/05の肺炎·風邪感 染死者は、1034人。
2011/第10週の03/06ー03/12の肺炎·風邪感染死者は、 1038人。
2011/第11週の03/13ー03/19の肺炎·風邪感 染死者は、1001人。
2011/第12週の03/20ー03/26の肺炎·風邪感染死者は 、1069人
2011/第13週の03/27ー04/02の肺炎·風邪感 染死者は、0995人。
2011/第14週の04/03ー04/09の肺炎·風邪感染死者は、 0975人。
2011/第15週の04/10ー04/16の肺炎·風邪感 染死者は、0851人。
2011/第16週の04/17ー04/23の肺炎·風邪感染死者は、 0857人。
2011/第17週の04/24ー04/30の肺炎·風邪感 染死者は、0778。
2011/第18週の05/01ー05/07の肺炎·風邪感染死者は、 0842人
2011/第19週の05/08---05/14の肺炎·風邪感染死者は、 0825人
2011/第20週の05/15---05/21の肺炎·風邪感染死者は、 0819人
2011/第21週の05/22ー05/28の肺炎·風邪感染死者は、 0773人
2011/第22週の05/29---06/04の肺炎·風邪感染死者は、 0674人
Update: Influenza Activity --- United states, 2010-- 2011 Season, and Composition of the 2011 --2012 Influenza Vaccine
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6021a5.htm?s_cid=mm6021a5_w
アメリカ合衆国の2010年ー2011年感染流行期のインフルエンザ風邪感染状況のまとめ
2011/第23週の06/05---06/11の肺炎·風邪感染死者は、 0776人
2011/第24週の06/12---06/18の肺炎·風邪感染死者は、 0737人
2011/第25週の06/19---06/25の肺炎·風邪感染死者は、 0727人
2011/第26週の06/26---07/02の肺炎·風邪感染死者は、 0674人
2011/第27週の07/03ー07/09の肺炎·風邪感染死者は、 0571人
2011/第28週の07/10---07/16の肺炎·風邪感染死者は、 0685人
2011 / 29th Week 07/17--07/23 肺炎·風邪感染死者は, 0723
2011 / 30th Week 07/24--07/30 肺炎·風邪感染死者は, 0721
2011 / 31st Week 07/31--08/06- 肺炎·風邪感染死者は, 0616
2011 / 32nd Week 08/07--08/13-肺炎·風邪感染死者は, 0614
2011 / 33rd Week 08/14--08/20 肺炎·風邪感染死者は, 0616
2011 (34th) Week 08/21--08/27-肺炎·風邪感染死者は, 0619

アメリカ合衆国の2010年ー2011年感染流行期の2010年第35週08月29日ー09月04日から、 2011年第34週08/21ー08/27までのインフルエンザ風邪感染死者数=36'438+3'909=40'347
報告漏れがあるので、実際の2010年/2011年の風邪流行季節の122都市の肺炎·風邪インフルエンザ感染死者数=2010年第35週08月29日ー09月04日からの 2011年第34週08/21ー08/27までの, 肺炎·インフルエンザ感染死者数の総数は、44'000人にはなるだろう。2次感染などによる間
接的なインフルエンザ風邪感染死者も含めると、最高 89'000人にはなるだろう。

********************************************************************************

アメリカ合州国の2011年/2012年の風邪流行季節の122都市の肺炎·風邪インフルエンザ感染死者数=2011年第35週08月28日ー09月03日から2012年第34週07/29ー08/04までの、アメリカ合州国の肺炎·風邪インフルエンザ感染死者数の総計は、37'057.

2011/第35週の08/28ー09/03の風邪感 染死者は、600人。[総計0'600] /全死者数
2011/第36週の09/04ー09/10の風邪感染死者は、 630人。[総計1'230]./全死者数
2011/第37週の09/11ー09/17の風邪感染死者は、672人。[総計1'902]./ 全死者数
2011/第38週の09/18ー09/24の風邪感染死者は、 681人。[総計2'583]./全死者数
2011/第39週の09/25ー10/01の風邪感染死者は、677人。`[総計3'260]./ 全死者数
2011/第40週の10/02ー10/08の風邪感染死者は、 587人. [総計 3'847] /全死者数
2011/第41週の10/09ー10/15の風邪感染死者は、637人。[総計4'484]./全死者数
2011/第42週の10/16ー10/22の風邪感染死者は、 677人。[総計5'161]/全死者数
2011/第43週の10/23ー10/29の風邪感染死者は、675人。[総計5'836]./全死者数
2011/第44週の10/30ー11/05の風邪感染死者は、 690人。[総計6'526]./全死者数
2011/第45週の11/06ー11/12の風邪感 染死者は、607人。[総計7'133]./全死者数
2011/第46週の11/13ー11/19の風邪感染死者は 、753人. [総計7'886]/全死者数
2011/第47週の11/20ー11/26の風邪感 染死者は、536人。[総計8'422]./全死者数
2011/第48週の11/27ー12/03の風邪感染死者は、 801人。[総計9'223]./全死者数
2011/第49週の12/04ー12/10の風邪感 染死者は、744人。[総計9'967]./全死者数
2011/第50週の12/11ー12/17の風邪感染死者は、 764人. [総計 10'731]/全死者数
2011/第51週の12/18ー12/24の風邪感 染死者は、719。 [総計 11'450]./全死者数
2011/第52週の12/25ー12/31の風邪感染死者は、 667人 [総計 12'117]./全死者数

2012/第01週の01/01---01/07の肺炎·風邪感染死者は、 0781人 [総計12'898]./全死者数
2012/第02週の01/08---01/14の肺炎·風邪感染死者は、 0922人 [総計13'820]/全死者数
2012/第03週の01/15ー01/21の肺炎·風邪感染死者は、 0878人.[総計14'698]./全死者数
2012/第04週の01/22ー01/28の肺炎·風邪感 染死者は、0917。 [総計15'615]./全死者数
2012/第05週の01/29ー02/04の肺炎·風邪感染死者は, 0 923人 [総計16'538]./全死者数
2012/第06週の02/05---02/11の肺炎·風邪感染死者は、 0754人 [総計17'292]./全死者数
2012/第07週の02/12---02/18の肺炎·風邪感染死者は、 0857人 [総計18'149]./全死者数
2012/第08週の02/19---02/25の肺炎·風邪感染死者は、 0832人 [総計18'981]./全死者数

2012/第09週の02/26---03/03の肺炎·風邪感染死者は、 0901人 [総計19'882]./全死者数

2012/第10週の03/04ー03/10の肺炎·風邪感染死者は、 0855人[総計 20'737]./全死者数
2012/第11週の03/11ー03/17の肺炎·風邪感 染死者は、0864。 [総計21'601]./全死者数
2012/第12週の03/18ー03/24の肺炎·風邪感染死者は, 0891人 [総計22'492]./全死者数
2012/第13週の03/25---03/31の肺炎·風邪感染死者は、 0778人 [総計23'270]./全死者数
2012/第14週の04/01---04/07の肺炎·風邪感染死者は、 0727人 [総計23'997]./全死者数
2012/第15週の04/08ー04/14の肺炎·風邪感染死者は、 0774人[総計 24'771]./全死者数
2012/第16週の04/15ー03/21の肺炎·風邪感 染死者は、0765。[総計 25'536]./全死者数

2012/第17週の04/22ー04/28の肺炎·風邪感染死者は, 0794人 [総計 26'330]. /全死者数
2012/第18週04/29-05/05肺炎·風邪感染死者0718人 [総計27'048],(風邪死者は全死者数の6'93%)

/2012第18週全死者数; 10'361, <65 01-24="" 01="" 206="" 25-44="" 2="" 45-64="" 581="" 6="">; 195
2012/第19週05/06-05/12肺炎·風邪感染死者0655人[総計27'703], (風邪死者は全死者数の6'12%)

/ 2012第19週全死者数; 10'707,<65: 01-24="" 1="" 210="" 25-44="" 2="" 45-64="" 634="" 7="">; 186
2012/第20週05/13-05/19肺炎·風邪感染死者0685人[総計28'388], (風邪死者は全死者数の6'38%)

/ 2012第20週全死者数; 10'728,<65: 01-24="" 1="" 229="" 25-44="" 2="" 45-64="" 613="" 7="">; 210
2012/第21週05/20-05/26肺炎·風邪感染死者0706人[総計29'094], (風邪死者は全死者数の6'59%)

/ 2012第21週全死者数; 10'709,<65: 01-24="" 1="" 228="" 25-44="" 2="" 45-64="" 612="" 7="">; 185

2012/第22週05/27-06/02肺炎·風邪感染死者0553人[総計29'647], (風邪死者は全死者数の5'99%)

/ 2012第22週全死者数; 09'228,<65: 01-24="" 1="" 228="" 25-44="" 2="" 45-64="" 565="" 6="">; 190

2012/第23週06/03-06/09肺炎·風邪感染死者0707人[総計30'354], (風邪死者は全死者数の6'28%)

/ 2012第23週全死者数; 11'260,<65: 01-24="" 1="" 240="" 25-44="" 2="" 45-64="" 678="" 7="">; 192

2012/第24週06/10-06/16肺炎·風邪感染死者0634人[総計30'988], (風邪死者は全死者数の6'28%)

/ 2012第24週全死者数; 10'091,<65: 01-24="" 1="" 224="" 25-44="" 2="" 45-64="" 631="" 6="">; 168

2012/第25週06/17-06/23肺炎·風邪感染死者0646人[総計31'634], (風邪死者は全死者数の6'11%)

/ 2012第25週全死者数; 10'578,<65: 01-24="" 1="" 217="" 25-44="" 2="" 45-64="" 634="" 7="">; 174

2012/第26週06/24-06/30肺炎·風邪感染死者0675人[総計32'309], (風邪死者は全死者数の6'56%)

/ 2012第26週全死者数; 10'283,<65: 01-24="" 1="" 248="" 25-44="" 2="" 45-64="" 632="" 6="">; 183

2012/第27週07/01-07/07肺炎·風邪感染死者0539人[総計32'848], (風邪死者は全死者数の6'10%)

/ 2012第27週全死者数; 08'832,<65: 01-24="" 182="" 1="" 25-44="" 2="" 45-64="" 492="" 5="">; 164

2012/第28週07/08-07/14肺炎·風邪感染死者0644人[総計33'492], (風邪死者は全死者数の5'96%)

/ 2012第28週全死者数; 10'805,<65: 01-24="" 1="" 25-44="" 284="" 2="" 45-64="" 664="" 7="">; 198
2012/第29週07/15-07/21肺炎·風邪感染死者0592人[総計34'084], (風邪死者は全死者数の5'62%)

/ 2012第29週全死者数; 10'541,<65: 01-24="" 1="" 25-44="" 253="" 2="" 45-64="" 659="" 6="">; 200

2012/第30週07/22-07/28肺炎·風邪感染死者0575人[総計34'659], (風邪死者は全死者数の5'62%)

/ 2012第30週全死者数; 10'237,<65: 01-24="" 1="" 25-44="" 271="" 2="" 45-64="" 642="" 6="">; 191

2012/第31週07/29-08/04肺炎·風邪感染死者0585人[総計35'244], (風邪死者は全死者数の5'79%)

???/ 2012第31週全死者数; 10'107,<65: 01-24="" 1="" 247="" 25-44="" 2="" 45-64="" 604="" 6="">; 196

2012/第032週の08/05-08/11の肺炎·風邪感染死者は、 0588人 [総計35'832]/全死者数
2012第32週全死者数; 10'274,<65: 01-24="" 1="" 238="" 25-44="" 2="" 45-64="" 602="" 6="">; 178

2012/第033週の08/12ー08/18の肺炎·風邪感染死者は、 0616人.[総計36'448]./全死者数
2012第33週全死者数; 10'170,<65: 01-24="" 194="" 1="" 25-44="" 2="" 45-64="" 604="" 6="">; 184

2012/第34週の08/19ー08/25の肺炎·風邪感 染死者は、0609。 [総計37'057]./全死者数
2012第34週全死者数; 10'934,<65: 01-24="" 1="" 25-44="" 252="" 2="" 45-64="" 692="" 7="">; 233


アメリカ合衆国の2011年ー2012年感染流行期の2011年第35週08月28日ー09月03日から、 2012年第34週08/19ー08/25までのインフルエンザ風邪感染死者数=37'057
報告漏れがあるので、実際の2011年/2012年の風邪流行季節の122都市の肺炎·風邪インフルエンザ感染死者数=2011年第35週08月28日ー09月03日から 2012年第34週08/19ー08/25までの, 肺炎·インフルエンザ感染死者数の総数は、41'000人にはなるだろう。2次感染などによる間
接的なインフルエンザ風邪感染死者も含めると、最高 82'000人にはなるだろう。

January 13, 2012 / Vol.61 / no.1
·QuickStats : Death Rate from Suicide for Persons Aged 45-64 Years, by Black or White Race and sex - United states, 1999 - 2008
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6101a6.htm?s_cid=mm6101a6_w

February 24, 2012 / Vol. 61 / No. 07 / pg. 113 - 132
·Influenza Vaccination Coverage Among Pregnant Women - 29 States and New York city, 2009-2010 Season
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6107a1.htm?s_cid=mm6107a1_w

·Update : Influenza Activity --- United States, October 2, 2011 - February 11, 2012

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6107a3.htm?s_cid=mm6107a3_w

April 6, 2012 / Vol.61 / No.13
·Influenza Outbreaks at Two Correctional Facilities, Maine, March 2011
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6113a3.htm?s_cid=mm6113a3_w

April 13, 2012 / Vol.61 / No.14
·Antibodies Cross-Reactive to Influenza A(H3N2) Variant Virus and Impact of 2010-2011 seasonal Influenza Vaccine on Cross-Reactive Antibodies - United States
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6114a1.htm?s_cid=mm6114a1_w


April 27, 2012 & Vol.61 & No.16
·Severe Coinfection with seasonal Influenza A(H3N2) Virus and Staphylococcus aureus - Maryland, February - March 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6116a4.htm?s_cid=mm6116a4_w

June 08, 2012 / Vol. 61 / No. 61 / No. 22

· Update : Influenza Activity -- United States, 2011-2012 season and composition of the 2012-13 Influenza Vaccine

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6122a4.htm?s_cid=mm6122a4_w

July 27, 2012 & Vol.61 & No.29
·Notes fron the Field : Outbreak of influenza A(H3N2) Virus Among Persons and Swine at a County Fair - Indiana, July 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6129a5.htm?s_cid=mm6129a5_w

August 17, 2012 / Vol.61 / No.32
· Prevention and Control of Influenza with Vaccines : Recommendationes of the Adversory Committee on ImmunizationPractices (ACIP) - United Staes, 2012 - 2013 Influenza Season

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6132a3.htm?s_cid=mm6132a3_w

· Evaluation of Rapid Influenza Diagnostic Tests for Influenza A (H3N2) v Virus and Updated Case Count - United States, 2012

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6132a4.htm?s_cid=mm6132a4_w

August 24, 2012 / Vol.61 / No.33
·Quick Stats : Rate of Hospitalization for Pneumonia by Age Group National Hospital Discharge Survey, United Staes, 2000 - 2010

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6133a4.htm?s_cid=mm6133a4_w









\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\

アメリカ合州国の2012年/2013年の風邪流行季節の122都市の肺炎·風邪インフルエンザ感染死者数=2012年第35週08月26日ー09月01日から、今までの 2013年第10週03/03ー03/09までの、アメリカ合州国の肺炎·風邪インフルエンザ感染死者数の報告総計は、22'823.


2012/第35週08/26-09/01肺炎·風邪感染死者 0594人 [総計00'594]./風邪死者は全死者の5'57%数
2012第35週全死者数; 10'669,<65: 01-24="" 1="" 224="" 25-44="" 2="" 45-64="" 660="" 7="">; 202

2012/第36週09/02-09/08肺炎·風邪感染死者 0588人 [総計01'182]./風邪死者は全死者の5'95%数
2012第36週全死者数; 9'874,<65: 01-24="" 1="" 224="" 25-44="" 2="" 45-64="" 622="" 6="">; 181

2012/第37週09/12-09/15肺炎·風邪感染死者 0691人 [総計1'873]./風邪死者は全死者の6'27%数
2012第37週全死者数; 11'016,<65: 01-24="" 1="" 243="" 25-44="" 2="" 45-64="" 642="" 7="">; 197

2012/第38週09/16-09/22肺炎·風邪感染死者 0648人 [総計2'521]./風邪死者は全死者の6'15%数
2012第38週全死者数; 10'537,<65: 01-24="" 1="" 238="" 25-44="" 2="" 45-64="" 583="" 6="">; 214

2012/第39週09/23-09/29肺炎·風邪感染死者 0691人 [総計3'212]./風邪死者は全死者の6'25%数
2012第39週全死者数; 11'048,<65: 01-24="" 1="" 215="" 25-44="" 2="" 45-64="" 598="" 7="">; 198

2012/第40週09/30-10/06肺炎·風邪感染死者 0623人[総計 3'835]./風邪死者は全死者の5'90%数
2012第40週全死者数; 10'562,<65: 01-24="" 1="" 228="" 25-44="" 2="" 45-64="" 621="" 6="">; 193

2012/第41週10/07-10/13肺炎·風邪感 染死者0636。 [総計4'471]./風邪死者は全死者の6' 28%数
2012第41週全死者数; 10'117,<65: 01-24="" 1="" 208="" 25-44="" 2="" 45-64="" 580="" 6="">; 160

2012/第42週10/14-10/20肺炎·風邪感染死者 0679人 [総計5'150]./風邪死者は全死者数の5'70%
2012第42週全死者数; 11'899,<65: 01-24="" 1="" 248="" 25-44="" 2="" 45-64="" 696="" 7="">; 234

2012/第43週10/21-10/27肺炎·風邪感染死者 0638人 [総計5'788]./風邪死者は全死者の6'50%数
2012第43週全死者数; 09'816,<65: 01-24="" 194="" 1="" 25-44="" 2="" 45-64="" 568="" 6="">; 171

2012/第44週04/01-04/07肺炎·風邪感染死者 0681人 [総計6'469]./風邪死者は全死者の6'59%数\

2012第44週全死者数; 10'336,<65: 01-24="" 1="" 229="" 25-44="" 2="" 45-64="" 580="" 6="">; 191

2012/第45週11/04-11/10肺炎·風邪感染死者0724人[総計 7'193]./風邪死者は全死者の6'38%数
2012第45週全死者数; 11'348,<65: 01-24="" 1="" 228="" 25-44="" 2="" 45-64="" 614="" 7="">; 200

2012/第46週11/11-11/17肺炎·風邪感 染死者0687 [総計 7'880]./風邪死者は全死者の6'40%数
2012第46週全死者数; 10'724,<65: 01-24="" 1="" 208="" 25-44="" 2="" 45-64="" 616="" 7="">; 190

2012/第47週11/18-11/24肺炎·風邪感染死0549人 [総計 08'429]. /風邪死者は全死者数の6'93%
2012第47週全死者数; 08'773,<65: 01-24="" 161="" 1="" 25-44="" 45-64="" 497="" 5="">; 149

2012/第48週11/25-12/01肺炎·風邪感染死者0812人 [総計09'241],(風邪死者は全死者数の6'93%)

/2012第48週全死者数; 12'466, <65 01-24="" 01="" 25-44="" 260="" 2="" 45-64="" 700="" 8="">; 197

2012/第49週12/02-12/08肺炎·風邪感染死者0739人[総計09'980], (風邪死者は全死者数の6'12%)

/ 2012第49週全死者数; 11'627,<65: 01-24="" 1="" 234="" 25-44="" 2="" 45-64="" 613="" 7="">; 203

2012/第50週12/09-12/15肺炎·風邪感染死者0783人[総計10'763], (風邪死者は全死者数の6'38%)

2012第50週全死者数; 11'651,<65: 01-24="" 1="" 237="" 25-44="" 2="" 45-64="" 642="" 7="">; 204

2012/第51週12/16-12/22肺炎·風邪感染死者0676人[総計11'439], (風邪死者は全死者数の6'38%)
2012第51週全死者数; 10'396,<65: 01-24="" 167="" 1="" 25-44="" 2="" 45-64="" 556="" 7="">; 181

2012/第52週12/23-12/29肺炎·風邪感染死者0523人[総計11'962], (風邪死者は全死者数の6'38%)
2012第52週全死者数; 07'484,<65: 01-24="" 124="" 1="" 25-44="" 444="" 45-64="" 5="">; 102

2013/第01週12/30-01/05肺炎·風邪感染死者0801人[総計12'763], (風邪死者は全死者数の6'27%)
2013第01週全死者数; 10'984,<65: 01-24="" 192="" 1="" 25-44="" 2="" 45-64="" 593="" 7="">; 153

2013/第02週01/06-01/12肺炎·風邪感染死者 1213人 [総計13'976]./風邪死者は全死者数の8'68%
2013第02週全死者数; 14'678,<65: 01-24="" 10="" 1="" 25-44="" 298="" 3="" 45-64="" 784="">; 219

2013/第03週01/13-01/19肺炎·風邪感染死者 1373人 [総計15'349]./風邪死者は全死者の8'94%
2013第03週全死者数; 13'973,<65: 01-24="" 1="" 241="" 25-44="" 3="" 45-64="" 683="" 9="">; 195

2013/第04週01/20-01/26肺炎·風邪感染死者 1'213人 [総計16'562]./風邪死者は全死者の9'41%\

2013第04週全死者数; 12'883,<65: 01-24="" 1="" 233="" 25-44="" 2="" 45-64="" 648="" 8="">; 178

2013/第05週01/27-02/02肺炎·風邪感染死者1246人[総計 17'1808]./風邪死者は全死者の8'99%数
2013第05週全死者数; 13'852,<65: 01-24="" 1="" 25-44="" 251="" 3="" 45-64="" 696="" 9="">; 195

2013/第06週02/03-02/09肺炎·風邪感 染死者1'125 [総計18'933]./風邪死者は全死者の9'07%数
2013第06週全死者数; 12'407,<65: 01-24="" 1="" 223="" 25-44="" 2="" 45-64="" 650="" 8="">; 196

2013/第07週02/10-02/16肺炎·風邪感染死1077人 [総計 20'010]. /風邪死者は全死者数の8'55%
2013第07週全死者数; 12'591,<65: 01-24="" 1="" 215="" 25-44="" 2="" 45-64="" 642="" 8="">; 156

2013/第08週02/17-02/23 肺炎·風邪感染死者0947人 [総計20'957],(風邪死者は全死者数の8'36%)

/2032第08週全死者数; 11'325, <65 01-24="" 01="" 188="" 25-44="" 2="" 45-64="" 578="" 7="">; 189

2013/第09週02/24-03/02肺炎·風邪感染死者0940人[総計21'897], (風邪死者は全死者数の7'73%)

/ 2013第09週全死者数; 12'157,<65: 01-24="" 1="" 222="" 25-44="" 2="" 45-64="" 630="" 8="">; 207

2013/第10週03/03-03/09 肺炎·風邪感染死者0926人[総計22'823], (風邪死者は全死者数の7'60%)

2013第10週全死者数; 12'182,<65: 01-24="" 1="" 207="" 25-44="" 2="" 45-64="" 631="" 8="">; 191

アメリカ合州国の2012年/2013年の風邪流行季節の122都市の肺炎·風邪インフルエンザ感染死者数=2012年第35週08月26日ー09月01日から、今までの 2013年第10週03/03--03/09までの、アメリカ合州国の肺炎·風邪インフルエンザ感染死者数の報告総計は、22'823
報告漏れがあるので、実際の2012年/2013年の風邪流行季節の122都市の肺炎·風邪インフルエンザ感染死者数=2012年第35週08月26日ー09月01日から、今までの 2013年第10週03/03ー03/09までの, 肺炎·インフルエンザ感染死者数の総数は、25'100人にはなるだろう。2次感染などによる間接的なインフルエンザ風邪感染死者も含めると、最高 50'200人にはなるだろう。
-----------------------------------------------------------------------------------------------------


Feburuary 22, 2013 & Vol.62 / No.

· Update : Influenza Activity - United States, September 30, 2012 - February 09, 2013

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6207a3.htm?s_cid=mm6207a3_w

January 18, 2013

· Early Estimates of of Seasonal Infulenza Vaccine Effectiveness, January 2013

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6202a4.htm?s_cid=mm6202a4_w

December 7, 2012 / Vol.61 / No.48
·Update : Influenza activity - United states, september 30 - November 24, 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6148a3.htm?s_cid=mm6148a3_w

November 30, 2012 / Vol.61 / No.47
·Announcement : National Influenza Vaccination week - December 2-8, 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6147a6.htm?s_cid=mm6147a6_w

November 9, 2012 / Vol.61 / No.44
·Announcement : World Pneumonia Day - November 12, 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6144a6.htm?s_cid=mm6144a6_w

November 2, 2012 / Vol.61 / No.43
·Evaluation of 11 Commercially Available Rapid Influenza Diagnostic Tests - United states, 2011-2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6143a3.htm?s_cid=mm6143a3_w

October 12, 2012 / Vol.61 / No.40
·QuickStates : Percentage of Hospitalizations Ending in death, by Selected First-Listed Diagnoses - National Hospital Discharge Survey, United States 2000 and 2010
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6140a8.htm?s_cid=mm6140a8_w

October 5, 2012 / Vol.61 / No.39
·Update: Influenza Activity - United States and Worldwide, May 20, 2012 - September 22, 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6139a3.htm?s_cid=mm6139a3_w

September 28, 2012 / Vol.61 / No.38
·Influenza Vacination Coverage Among Health-Care Personal - 2011-2012 Influenza Season, United States
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6138a1.htm?s_cid=mm6138a1_w

·Influenza Vaccination Coverage Among Pregnant Women - 2011-2012 Influenza Season, United States
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6138a2.htm?s_cid=mm6138a2_w

·Influenza A(H3N2) Variant Virus - Related Hospitalizations - Ohio, 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6138a3.htm?s_cid=mm6138a3_w

·Announcements : Final State-Level 2011-2012 Influenza Vaccination Coverage Estimates Available Online
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6138a5.htm?s_cid=mm6138a5_w


September 14, 2012 / Vol.61 / No.36
·Notes from the Field : Highly Pathogenic Avian Influenza A(H7N3) Virus Infection in Two Poultry Workers - Jalisco, Mexico, July 2012

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6136a4.htm?s_cid=mm6136a4_w

August 17, 2012 / Vol.61 / No.32
· Prevention and Control of Influenza with Vaccines : Recommendationes of the Adversory Committee on ImmunizationPractices (ACIP) - United Staes, 2012 - 2013 Influenza Season

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6132a3.htm?s_cid=mm6132a3_w

· Evaluation of Rapid Influenza Diagnostic Tests for Influenza A (H3N2) v Virus and Updated Case Count - United States, 2012

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6132a4.htm?s_cid=mm6132a4_w

August 24, 2012 / Vol.61 / No.33
·Quick Stats : Rate of Hospitalization for Pneumonia by Age Group National Hospital Discharge Survey, United Staes, 2000 - 2010

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6133a4.htm?s_cid=mm6133a4_w

July 27, 2012 & Vol.61 & No.29
·Notes fron the Field : Outbreak of influenza A(H3N2) Virus Among Persons and Swine at a County Fair - Indiana, July 2012

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6129a5.htm?s_cid=mm6129a5_w



June 08, 2012 / Vol. 61 / No. 61 / No. 22

· Update : Influenza Activity -- United States, 2011-2012 season and composition of the 2012-13 Influenza Vaccine

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6122a4.htm?s_cid=mm6122a4_w

April 27, 2012 & Vol.61 & No.16
·Severe Coinfection with seasonal Influenza A(H3N2) Virus and Staphylococcus aureus - Maryland, February - March 2012
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6116a4.htm?s_cid=mm6116a4_w

April 13, 2012 / Vol.61 / No.14
·Antibodies Cross-Reactive to Influenza A(H3N2) Variant Virus and Impact of 2010-2011 seasonal Influenza Vaccine on Cross-Reactive Antibodies - United States
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6114a1.htm?s_cid=mm6114a1_w

April 6, 2012 / Vol.61 / No.13
·Influenza Outbreaks at Two Correctional Facilities, Maine, March 2011
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6113a3.htm?s_cid=mm6113a3_w

September 16,2011 / V0l.60 / N0. 36 /Pg. 1233--1268
. Update : Influenza Activity --- United States and Wordwide, May 22--September 3, 2011
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6036a2.htm?s_cid=mm6036a2_w

February 24, 2012 / Vol. 61 / No. 07 / pg. 113 - 132
·Influenza Vaccination Coverage Among Pregnant Women - 29 States and New York city, 2009-2010 Season
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6107a1.htm?s_cid=mm6107a1_w

·Update : Influenza Activity --- United States, October 2, 2011 - February 11, 2012

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6107a3.htm?s_cid=mm6107a3_w

December 9, 2011 / Vol. 60 / No. 48 / Pg. 1641 - 1672
. Update : Influenza Activity --- United States, October -- November 26, 201
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6048a2.htm?s_cid=mm6048a2_w

February 24, 2012 / Vol. 61 / No. 07 / pg. 113 - 132

·Update : Influenza Activity --- United States, October 2, 2011 - February 11, 2012

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6107a3.htm?s_cid=mm6107a3_w

Early Estimates of Seasonal Influenza Vaccine Effectiveness in the United States in January 2013

CDC

Centers for Disease Cntrol and Prevention

Morbidity and Mortakity Weekly Report

published on January 18, 2013

# Early Estimates of Seasonal Influenza Vaccine Effectiveness in the United States in January 2013

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6202a4.htm?s_cid=mm6202a4_w

Update : Influenza Activity - United States from September 30, 2012 to February 9, 2013

CDC

Centers for Disease Control and Prevention

Morbidity and Mortality Weekly Report

published on February 22, 2013

Update : Influenza Activity - United States from September 30, 2012 to February 9, 2013

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6207a3.htm?s_cid=mm6207a3_w

Update: Influenza Activity — United States, September 30, 2012–February 9, 2013

Weekly

February 22, 2013 / 62(07);124-130

Influenza activity in the United States began to increase in mid-November and remained elevated through February 9, 2013. During that time, influenza A (H3N2) viruses predominated overall, followed by influenza B viruses. This report summarizes U.S. influenza activity* since the beginning of the 2012–13 influenza season and updates the previous summary (1).
Viral Surveillance
During September 30, 2012–February 9, 2013, approximately 140 World Health Organization (WHO) and National Respiratory and Enteric Virus Surveillance System collaborating laboratories in the United States tested 203,706 respiratory specimens for influenza viruses; 55,470 (27.2%) were positive (Figure 1). Of these, 44,035 (79%) were influenza A viruses, and 11,435 (21%) were influenza B viruses. Of the 44,035 influenza A viruses, 29,914 (68%) were subtyped; 29,091 (97%) of these were influenza A (H3) viruses, and 823 (3%) were influenza A (H1N1)pdm09 (pH1N1) viruses. The percentage of specimens testing positive for influenza increased through the week ending December 29, 2012 (week 52), when 38.1% tested positive, and decreased subsequently. In the week ending February 9, 2013 (week 6), 19.7% of specimens tested positive. Since the start of the influenza season to February 9, 2013, influenza A (H3) viruses predominated in the United States overall, followed by influenza B viruses, while pH1N1 viruses were identified less frequently.
Novel Influenza A Viruses
One infection with an influenza A (H3N2) variant virus (H3N2v) was reported to CDC during the week ending December 8, 2012 (week 49) from Minnesota. Close contact between the patient and swine in the week preceding illness was reported. The patient fully recovered, and no further cases were identified in contacts of the patient. This is the second H3N2v infection reported for the 2012–13 influenza season (1).
Antigenic Characterization
WHO collaborating laboratories in the United States are requested to submit a subset of their influenza-positive respiratory specimens to CDC for further antigenic characterization. CDC has antigenically characterized 1,088 influenza viruses collected during the 2012–13 season, including 86 pH1N1, 677 influenza A (H3N2), and 325 influenza B viruses. All pH1N1 viruses were characterized as A/California/7/2009-like (H1N1), which is the 2012–13 influenza A (H1N1) component of the 2012–13 Northern Hemisphere vaccine. A total of 673 (99.4%) of the 677 influenza A (H3N2) viruses were characterized as A/Victoria/361/2011-like (H3N2), the influenza A (H3N2) component of the 2012–13 Northern Hemisphere vaccine. Of the 325 influenza B viruses tested, 230 (71%) belong to the B/Yamagata lineage and were characterized as B/Wisconsin/1/2010-like, the influenza B component of the 2012–13 Northern Hemisphere vaccine; 95 (29%) of the influenza B viruses tested belong to the B/Victoria lineage of viruses.
Antiviral Resistance of Influenza Virus Isolates
Since October 1, 2012, a total of 1,702 influenza viruses have been tested for resistance to influenza antiviral medications. None of the 1,072 influenza A (H3N2) or the 396 influenza B viruses was resistant to either oseltamivir or zanamivir. Among 234 pH1N1 viruses tested for resistance to oseltamivir, two (0.9%) were found to be resistant, and of the 97 viruses tested for resistance to zanamivir, none were found to be resistant, including one of the two oseltamivir-resistant pH1N1 viruses. Additional laboratory testing, including testing for resistance to zanamvir, is pending on the second oseltamivir-resistant pH1N1 virus. High levels of resistance to the adamantanes persist among pH1N1 and influenza A (H3N2) viruses.
Outpatient Illness Surveillance
Since September 30, 2012, the weekly percentage of outpatient visits for influenza-like illness (ILI)† reported by approximately 1,900 U.S. Outpatient ILI Surveillance Network (ILINet) providers in 50 states, New York City, Chicago, the U.S. Virgin Islands, and the District of Columbia that comprise ILINet, has ranged from 1.2% to 6.1%. From the week ending November 24, 2012 (week 47) to February 9, 2013 (week 6), the percentage equaled or exceeded the national baseline§ of 2.2% for 12 consecutive weeks (Figure 2). During the 1997–98 through 2011–12 seasons, peak weekly percentages of outpatient visits for ILI ranged from 2.4% to 7.7% and remained above baseline levels for an average of 12 weeks (range: 1–18 weeks). For the week ending February 9, 2013 (week 6), all 10 U.S. Department of Health and Human Services regions¶ continued to report ILI activity above region-specific baseline levels.
Data collected in ILINet are used to produce a measure of ILI activity** by jurisdiction. During the week ending February 9, 2013 (week 6), 11 states and New York City experienced high ILI activity (Alabama, California, Idaho, Kansas, Michigan, Missouri, Nevada, New Jersey, Texas, Utah, and Vermont), 10 states experienced moderate ILI activity (Arizona, Colorado, Illinois, Indiana, Louisiana, Minnesota, North Dakota, Oregon, South Dakota, and Virginia), 13 states and the District of Columbia experienced low ILI activity (Arkansas, Florida, Georgia, Hawaii, Iowa, Massachusetts, Mississippi, Nebraska, New Mexico, New York, Oklahoma, Washington, and Wyoming), and 16 states experienced minimal ILI activity (Alaska, Connecticut, Delaware, Kentucky, Maine, Maryland, Montana, New Hampshire, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, West Virginia, and Wisconsin). As of February 9, 2013, the largest total number of jurisdictions experiencing high ILI activity in a single week occurred during the week ending December 29, 2012 (week 52), when a total of 33 states and New York City experienced high ILI activity. The total number of jurisdictions experiencing high ILI activity in a single week during the 2008–09 through 2011–12 influenza seasons has ranged from four to 18 jurisdictions, excluding the 2009 pandemic, when 44 jurisdictions reported high ILI activity (CDC, unpublished data, 2013).
Geographic Spread of Influenza
For the week ending February 9, 2013 (week 6), the geographic spread of influenza†† was reported as widespread in 31 states (Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Idaho, Illinois, Indiana, Iowa, Kansas, Maine, Maryland, Massachusetts, Michigan, Missouri, Montana, New Hampshire, New Jersey, New Mexico, New York, Ohio, Oklahoma, Oregon, Pennsylvania, Utah, Virginia, Washington, Wisconsin, and Wyoming), regional in Puerto Rico and 14 states (Alabama, Hawaii, Kentucky, Louisiana, Minnesota, Nebraska, Nevada, North Dakota, South Carolina, South Dakota, Tennessee, Texas, Vermont, and West Virginia), and local in the District of Columbia and four states (Georgia, Mississippi, North Carolina, and Rhode Island). Sporadic influenza activity was reported by Guam and one state (Delaware), and the U.S. Virgin Islands did not report. As of February 9, 2013, the number of jurisdictions reporting influenza activity as widespread peaked during the week ending January 12, 2013 (week 2), when a total of 48 jurisdictions reported influenza activity as widespread. The number of states reporting widespread activity during the peak week of activity has ranged from 25 to 49 states during the previous five influenza seasons (CDC, unpublished data, 2013).
Influenza-Associated Hospitalizations
CDC monitors hospitalizations associated with laboratory-confirmed influenza infection in adults and children through the Influenza Hospitalization Surveillance Network (FluSurv-NET),§§ which covers approximately 9% of the U.S. population. From October 1, 2012, to February 9, 2013, a total of 8,953 laboratory-confirmed influenza associated hospitalizations were reported, with a cumulative incidence for all age groups of 32.1 per 100,000 population. The most affected age group was persons aged ≥65 years, accounting for more than 50% of reported influenza-associated hospitalizations. The cumulative hospitalization rate (per 100,000 population) from October 1, 2012, to February 9, 2013, was 44.0 among children aged 0–4 years, 9.3 among children aged 5–17 years, 11.6 among adults 18–49 years, 29.4 among adults aged 50–64 years, and 146.2 among adults aged ≥65 years (Figure 3). During the past three influenza seasons (2009–10 through 2011–12), end-of-season age-specific cumulative hospitalization rates ranged from 14.8 to 73.0 per 100,000 population for ages 0–4 years, 4.0 to 27.3 for ages 5–17 years, 4.1 to 23.3 for ages 18–49 years, 8.3 to 30.4 for ages 50–64 years, and 25.3 to 64.0 for ages ≥65 years. During the 2005–06 to the 2008–09 influenza seasons, end-of-season hospitalization rates among adults aged ≥65 years ranged from 13.5 to 73.8 per 100,000 population.
For the current season, the most commonly reported underlying medical conditions among hospitalized adults were cardiovascular disease, metabolic disorders, obesity, and chronic lung disease (excluding asthma). The most commonly reported underlying medical conditions in hospitalized children were asthma, neurologic disorders, and immune suppression. Forty-four percent of hospitalized children had no identified underlying medical conditions that place them at higher risk for influenza complications.¶¶ Among 218 hospitalized women of childbearing age (15–44 years), 63 (29%) were pregnant.
Pneumonia and Influenza-Associated Mortality
For the week ending February 9, 2013 (week 6), pneumonia and influenza (P&I) was reported as an underlying or contributing cause of death for 9.1% of all deaths reported to the 122 Cities Mortality Reporting System (Figure 4). This percentage is above the epidemic threshold of 7.5% for that week.*** Since September 30, 2012, the weekly percentage of deaths attributed to P&I ranged from 5.8% to 9.9%, and, as of February 9, 2013 (week 6), had exceeded the epidemic threshold for 6 consecutive weeks (weeks ending January 5–February 9, 2013 [weeks 1–6]). As of February 9, 2013, the weekly percentage of deaths attributed to P&I peaked at 9.9% during the week ending January 19, 2013 (week 3). Peak weekly percentages of deaths attributed to P&I in the previous five seasons ranged from 7.9% for the 2008–09 and 2011–12 seasons to 9.1% during the 2007–08 and 2010–11 seasons.
Influenza-Associated Pediatric Mortality
As of February 9, 2013, a total of 64 laboratory-confirmed influenza-associated pediatric deaths occurring during the 2012–13 season had been reported to CDC from Chicago, New York City, and 27 states. The mean and median ages of children reported to have died were 7.9 and 7.4 years, respectively; three children were aged <6 months, 11 were aged 6–23 months, eight were aged 2–4 years, 24 were aged 5–11 years, and 18 were aged 12–17 years. Of the 64 deaths, 16 were associated with influenza A (H3N2) virus infection, 19 deaths were associated with an influenza A virus infection that was not subtyped, and 29 deaths were associated with influenza B infection. Since 2004, when CDC began collection of influenza-associated pediatric death data, each season approximately 20% of children aged ≥6 months who were eligible to receive seasonal influenza vaccination and died from influenza-associated complications had received the seasonal influenza vaccine (CDC, unpublished data, 2013). Since influenza-associated pediatric mortality became a nationally notifiable disease in 2004, the total number of influenza-associated pediatric deaths has ranged from 34 to 122 per season; excluding the 2009 pandemic, when 348 pediatric deaths were reported to CDC during April 15, 2009, through October 2, 2010.

Reported by

World Health Organization Collaborating Center for Surveillance, Epidemiology, and Control of Influenza. Lenee Blanton, MPH, Scott Epperson, MPH, Lynnette Brammer, MPH, Krista Kniss, MPH, Desiree Mustaquim, MPH, Craig Steffens, MPH, Alejandro Perez, MPH, Sandra S. Chaves, MD, Teresa Wallis, MS, Julie Villanueva, PhD, Xiyan Xu, MD, Lyn Finelli, DrPH, Anwar Isa Abd Elal, BScCS, Larisa Gubareva, PhD, Joseph Bresee, MD, Alexander Klimov, PhD, Nancy Cox, PhD, Influenza Div, National Center for Immunization and Respiratory Diseases, CDC. Corresponding contributor: Lenee Blanton, lblanton@cdc.gov, 404-639-3747.

Editorial Note

The 2012–13 influenza season began early, and influenza activity remained elevated across the United States as of February 9, 2013; during the most recent weeks, decreases have been observed in the South and East, while increases have continued in the West. Although the timing of influenza activity is not predictable, substantial activity can occur as late as May (2). During September 30, 2012–February 9, 2013, influenza A (H3N2) viruses were identified most frequently, followed by influenza B viruses, but a small number of pH1N1 viruses also were reported. Antigenic characterization of influenza-positive respiratory specimens submitted to CDC indicated that the majority of these specimens were like the 2012–13 influenza vaccine components. As of February 9, 2013, more than half of influenza-associated hospitalizations were reported to have occurred in adults aged ≥65 years, and rates of influenza-associated hospitalization among adults aged ≥65 years increased sharply from late December through January. The weekly percentage of deaths attributed to P&I was above the epidemic threshold beginning early in January, with the majority of the P&I deaths occurring in adults aged ≥65 years.
In the past, higher overall and age-specific rates of hospitalization and mortality have been observed during influenza A (H3N2)–predominant seasons (3,4). Based on FluSurv-Net surveillance data for the 2012–13 season to date, rates of influenza-associated hospitalizations are highest among adults aged ≥65 years, followed by children aged 0–4 years. This trend is similar to that observed in the 2007–08 and 2010–11 influenza seasons, during which influenza A (H3N2) viruses predominated. The number and rate of influenza-associated hospitalizations among adults aged ≥65 years during the 2012–13 influenza season is the highest since data collection on laboratory-confirmed influenza-associated hospitalization in adults began in the 2005–06 season.
Vaccination remains the first and best way to prevent influenza and its complications. Health-care providers should continue to offer vaccine to all unvaccinated persons aged ≥6 months throughout the influenza season. Interim vaccine effectiveness estimates suggest that effectiveness against influenza A (H3N2) viruses is lower and not statistically significant in adults aged ≥65 years during the 2012–13 influenza season (5). Adults aged ≥65 years are at the greatest risk for hospitalization and death from influenza-associated complications; therefore, it is important for them to receive their annual influenza vaccine, take everyday preventive actions, and seek medical care quickly if they develop ILI symptoms to see if treatment with antiviral medications is needed. Antiviral medications remain an important adjunct to vaccination for reducing the health impact of influenza. Recommended antiviral medications are oseltamivir and zanamivir. Early and aggressive treatment with antiviral medication is crucial, ideally within the first 48 hours of illness onset, and persons with suspected influenza infection who are at high risk, including adults aged ≥65 years, should be treated with antiviral medications without the need to wait for laboratory confirmation of influenza (6). However, as indicated by observational studies, antiviral treatment might still be beneficial in patients with severe, complicated, or progressive illness and in hospitalized patients when started after 48 hours of illness onset (6). Recent data on influenza antiviral resistance indicate that >99% of currently circulating influenza virus strains are sensitive to these medications.
Influenza surveillance reports for the United States are posted online weekly and are available at http://www.cdc.gov/flu/weekly. Additional information regarding influenza viruses, influenza surveillance, influenza vaccine, influenza antiviral medications, and novel influenza A infections in humans is available at http://www.cdc.gov/flu.

Acknowledgments

Participating state, city, county, and territorial health departments and public health laboratories; U.S. World Health Organization collaborating laboratories; the National Respiratory and Enteric Virus Surveillance System collaborating laboratories; the U.S. Outpatient Influenza-Like Illness Surveillance Network; the Influenza Hospitalization Surveillance Network; the Influenza-Associated Pediatric Mortality Surveillance System; and the 122 Cities Mortality Reporting System.

References

1. CDC. Update: influenza activity—United States, September 30–November 24, 2012. MMWR 2012;61:990–3.
2. CDC. Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2010;59(No. RR-8).
3. Dao CN, Kamimoto L, Nowell M, et al. Adult hospitalizations for laboratory-positive influenza during the 2005–2006 through 2007–2008 seasons in the United States. J Infect Dis 2010;202:881–8.
4. Thompson WW, Shay DK, Weintrab E, et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003;289:179–86.
5. CDC. Interim adjusted estimates of seasonal influenza vaccine effectiveness—United States, February 2013. MMWR 2013;62:120–4.
6. CDC. Antiviral agents for the treatment and chemoprophylaxis of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2011;60(No. RR-1).

* The CDC influenza surveillance system collects five categories of information from eight data sources: 1) viral surveillance (U.S. World Health Organization collaborating laboratories, the National Respiratory and Enteric Virus Surveillance System, and novel influenza A virus case reporting); 2) outpatient illness surveillance (U.S. Outpatient Influenza-Like Illness Surveillance Network); 3) mortality (122 Cities Mortality Reporting System and influenza-associated pediatric mortality reports); 4) hospitalizations (FluSurv-NET, which includes the Emerging Infections Program and surveillance in five additional states); and 5) summary of the geographic spread of influenza (state and territorial epidemiologist reports).

† Defined as a temperature ≥100°F (≥37.8°C), oral or equivalent, and cough or sore throat, without a known cause other than influenza.

§ The national and regional baselines are the mean percentage of visits for ILI during noninfluenza weeks for the previous three seasons plus two standard deviations. Noninfluenza weeks are defined as periods of 2 or more consecutive weeks in which each week accounted for less than 2% of the season's total number of specimens that tested positive for influenza. National and regional percentages of patient visits for ILI are weighted on the basis of state population. Use of the national baseline for regional data is not appropriate.

¶ The 10 regions include the following jurisdictions: Region 1: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont; Region 2: New Jersey, New York, Puerto Rico, and the U.S. Virgin Islands; Region 3: Delaware, District of Columbia, Maryland, Pennsylvania, Virginia, and West Virginia; Region 4: Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee; Region 5: Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin; Region 6: Arkansas, Louisiana, New Mexico, Oklahoma, and Texas; Region 7: Iowa, Kansas, Missouri, and Nebraska; Region 8: Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming; Region 9: Arizona, California, Hawaii, Nevada, American Samoa, Commonwealth of the Northern Mariana Islands, Federated States of Micronesia, Guam, Marshall Islands, and Republic of Palau; and Region 10: Alaska, Idaho, Oregon, and Washington.

** Activity levels are based on the percentage of outpatient visits in a state attributed to ILI and are compared with the average percentage of ILI visits that occur during weeks with little influenza virus circulation. Activity levels range from minimal, which would correspond to ILI activity from outpatient clinics being at or below the average, to high, which would correspond to ILI activity from outpatient clinics being much higher than the average.

†† Levels of activity are 1) no activity; 2) sporadic: isolated laboratory-confirmed influenza cases or a laboratory-confirmed outbreak in one institution, with no increase in activity; 3) local: increased ILI, or at least two institutional outbreaks (ILI or laboratory-confirmed influenza) in one region of the state, with recent laboratory evidence of influenza in that region; virus activity no greater than sporadic in other regions; 4) regional: increased ILI activity or institutional outbreaks (ILI or laboratory-confirmed influenza) in at least two but less than half of the regions in the state with recent laboratory evidence of influenza in those regions; and 5) widespread: increased ILI activity or institutional outbreaks (ILI or laboratory-confirmed influenza) in at least half the regions in the state, with recent laboratory evidence of influenza in the state.

§§ FluSurv-NET conducts population-based surveillance for laboratory-confirmed influenza-associated hospitalizations in children aged <18 years (since the 2003–04 influenza season) and adults aged ≥18 years (since the 2005–06 influenza season). The FluSurv-NET covers approximately 80 counties in the 10 Emerging Infections Program states (California, Colorado, Connecticut, Georgia, Maryland, Minnesota, New Mexico, New York, Oregon, and Tennessee) and additional Influenza Hospitalization Surveillance Project (IHSP) states. IHSP began during the 2009–10 season to enhance surveillance during the 2009 H1N1 pandemic. IHSP sites included Iowa, Idaho, Michigan, Oklahoma, and South Dakota during the 2009–10 season; Idaho, Michigan, Ohio, Oklahoma, Rhode Island, and Utah during the 2010–11 season; Michigan, Ohio, Rhode Island, and Utah during the 2011–12 season; and Iowa, Michigan, Ohio, Rhode Island, and Utah during the 2012–13 season. Incidence rates are calculated using CDC's National Center for Health Statistics population estimates for the counties included in the surveillance catchment area. Laboratory confirmation is dependent on clinician-ordered influenza testing, and testing for influenza often is underutilized because of the poor reliability of rapid test results and greater reliance on clinical diagnosis for influenza. As a consequence, cases identified as part of influenza hospitalization surveillance likely are an underestimation of the actual number of persons hospitalized with influenza.

¶¶ Persons at higher risk include children aged <5 years (especially those aged <2 years); adults aged ≥65 years; persons with chronic pulmonary (including asthma), cardiovascular (except hypertension alone), renal, hepatic, hematologic (including sickle cell disease), or metabolic disorders (including diabetes mellitus), or neurologic and neurodevelopment conditions (including disorders of the brain, spinal cord, peripheral nerve, and muscle, such as cerebral palsy, epilepsy [seizure disorders], stroke, intellectual disability [mental retardation], moderate to severe developmental delay, muscular dystrophy, or spinal cord injury); persons with immunosuppression, including that caused by medications or by human immunodeficiency virus infection; women who are pregnant or postpartum (within 2 weeks after delivery); persons aged ≤18 years who are receiving long-term aspirin therapy; American Indian/Alaska Natives; persons who are morbidly obese (i.e., body mass index ≥40); and residents of nursing homes and other chronic-care facilities.

*** The seasonal baseline proportion of P&I deaths is projected using a robust regression procedure in which a periodic regression model is applied to the observed percentage of deaths from P&I that were reported by the 122 Cities Mortality Reporting System during the preceding 5 years. The epidemic threshold is set at 1.645 standard deviations above the seasonal baseline.

What is already known on this topic?

CDC collects, compiles, and analyzes data on influenza activity year-round in the United States. The timing and severity of circulating influenza viruses can vary by geographic location and season.

What is added by this report?

Influenza activity in the United States began to increase in mid-November and remained elevated through February 9, 2013. During September 30, 2012–February 9, 2013, of 55,470 influenza viruses tested, 79% were influenza A, and 19% were influenza B. Of 29,914 influenza A viruses that were subtyped, 97% were H3N2, and 3% were pH1N1. The age group with the highest hospitalization rate was ≥65 years, accounting for more than half of all reported influenza-associated hospitalizations.

What are the implications for public health practice?

Year-round influenza surveillance provides critical information for planning interventions to prevent and control influenza, developing vaccine recommendations and antiviral treatment guidance, and presenting information to the public regarding the progress and severity of the influenza season.

FIGURE 1. Number and percentage of respiratory specimens testing positive for influenza, by type, surveillance week, and year — U.S. World Health Organization and National Respiratory and Enteric Virus Surveillance System collaborating laboratories, United States, 2012–13 influenza season

Alternate Text: The figure above shows the number and percentage of respiratory specimens testing positive for influenza, by type, surveillance week, and year in the United States, during the 2012-13 influenza season, according to U.S. World Health Organization (WHO) and National Respiratory and Enteric Virus Surveillance System (NREVSS) collaborating laboratories. During September 30, 2012-February 9, 2013, approxi¬mately 140 WHO and NREVSS collaborat¬ing laboratories in the U.S. tested 203,706 respiratory specimens for influenza viruses; 55,470 (27.2%) were positive.

FIGURE 2. Percentage of visits for influenza-like illness (ILI) reported by the U.S. Outpatient Influenza-Like Illness Surveillance Network (ILINet), by surveillance week and year — United States, 2012–13 and selected previous influenza seasons*

* Data as of February 16, 2013.

Alternate Text: The figure above shows the percentage of visits for influenza-like illness reported by the U.S. Outpatient Influenza-Like Illness Surveillance Network (ILINet), by surveillance week and year in the United States during 2012-13 and selected previous influenza seasons. From the week ending November 24, 2012 (week 47) to February 9, 2013 (week 6), the percentage equaled or exceeded the national baseline of 2.2% for 12 consecutive weeks.

FIGURE 3. Rates of hospitalization for laboratory-confirmed influenza, by age group and surveillance week — FluSurv-NET,* 2012–13 influenza season†

* FluSurv-NET conducts population-based surveillance for laboratory-confirmed influenza-associated hospitalizations in children aged <18 years (since the 2003–04 influenza season) and adults aged ≥18 years (since the 2005–06 influenza season). The FluSurv-NET covers approximately 80 counties in the 10 Emerging Infections Program states (California, Colorado, Connecticut, Georgia, Maryland, Minnesota, New Mexico, New York, Oregon, and Tennessee) and additional Influenza Hospitalization Surveillance Project states (Iowa, Michigan, Ohio, Rhode Island, and Utah).

† Data as of February 16, 2013.

Alternate Text: The figure above shows rates of hospitalization for laboratory-confirmed influenza, by age group and surveillance week, during the 2012-13 influenza season, according to FluSurv-NET. The cumulative hospitalization rate (per 100,000 population) from October 1, 2012 to February 9, 2013, was 43.9 among children aged 0-4 years, 9.3 among children aged 5-17 years, 11.6 among adults 18-49 years, 29.4 among adults aged 50-64 years, and 146.2 among adults aged ≥65 years.

FIGURE 4. Percentage of all deaths attributable to pneumonia and influenza (P&I), by surveillance week and year — 122 U.S. Cities Mortality Reporting System, United States, 2008–2013*

* For the reporting week ending February 9, 2013.

† The epidemic threshold is 1.645 standard deviations above the seasonal baseline.

§ The seasonal baseline is projected using a robust regression procedure that applies a periodic regression model to the observed percentage of deaths from P&I during the preceding 5 years.

Alternate Text: The figure above shows the percentage of all deaths attributable to pneumonia and influenza, by surveillance week and year, during 2008-2013, according to the 122 U.S. Cities Mortality Reporting System. For the week ending February 9, 2013 (week 6), pneumonia and influenza (P&I) was reported as an underlying or contrib¬uting cause of death for 9.1% of all deaths reported to the 122 Cities Mortality Reporting System. This percentage is above the epidemic threshold of 7.5% for that week.

Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of Health and Human Services. References to non-CDC sites on the Internet are provided as a service to MMWR readers and do not constitute or imply endorsement of these organizations or their programs by CDC or the U.S. Department of Health and Human Services. CDC is not responsible for the content of pages found at these sites. URL addresses listed in MMWR were current as of the date of publication.