ドイツ連邦(国立)疫病研究所
http://www.rki.de/
Information for EHEC / HUS outbreak events
published 05/07/2011, data as of 04/07/2011
http://www.rki.de/cln_151/nn_205760/DE/Home/Info-HUS.html
2011年07月05日火曜日10:00発表、2011年07月04日月曜日10:00現在の事実情報による
ドイツでは、2011年07月04日月曜日10:00現在、3'235人の病原性大腸菌(EHEC)感染患者が、確認されて、うち 17人が 感染死亡して、851人の出血性尿毒症症候群(HUS)感染患者が確認されて、うち 32人が、かんせんしぼうした。これで 病原性大腸菌(HEHEC)や出血性尿毒症症候群(HUS)の感染確認患者は、4'086人で、感染死亡患者は、49人になる。
これに、オーストリアの感染患者の5人、カナダの01人、チェコの1人、デンマークの23人、フランスの18+以上?人、ドイツの4¡086人と49人の感染死亡患者、ギリシアの1人、ルクセンブルグの2人、オランダの11人、ノルウェイの1人、ポーランドの3人、スペインの2人、スウェーデンの53人と感染死亡の1人、スイスの5人、イギリス の6人、アメリカ合衆国の6人と感染死亡の1人を加える[1]と、世界では、4'224人以上の病原性大腸菌感染患者(EHEC)と溶血性尿毒症症候群(HUS)の感染患者が確認されて、51人の感染死者がでた。
[1] Outbraks of E.coli O104:H4 infection
http://www.euro.who.int/en/what-we-do/health-topics/emergencies/international-health-regulations/outbreaks-of-e.-coli-o104h4-infection
Outbreaks od E.coli O104:H4 infection : update28
01-07-2011
http://www.euro.who.int/en/what-we-do/health-topics/emergencies/international-health-regulations/news/news/2011/07/outbreaks-of-e.-coli-o104h4-infection-update-28
Outbreaks of E. coli O104:H4 infection: update 28
01-07-2011
On 28 June 2011, the Institut de veille sanitaire, France, published new figures for the verocytotoxin-producing Escherichia coli (VTEC)/haemolytic uraemic syndrome (HUS) outbreak in the Bordeaux region in France, where in total 8 cases of bloody diarrhoea and 8 HUS cases have been reported since 22 June. E. coli O104:H4 infection has been confirmed in 4 of these cases. Also on 28 June, Sweden reported a confirmed case of E. coli O104:H4 infection in southern Sweden in an adult male. None of these patients in France or Sweden had travelled in Germany since 1 May 2011.In France, current results from the continuing investigations suggest that sprouted beans or sprouted seeds might be involved. In Sweden, the vehicle of infection remains under investigation.
On 30 June 2011, the Institut de veille sanitaire announced that the results of the analyses performed by the French national reference centre for E. coli and Shigella and its associated laboratory showed that the E. coli O104:H4 strain that caused the outbreak in Germany in May–June 2011 and the one causing the outbreak in France in June are genetically related. This strengthens the evidence pointing to a common source behind these outbreaks.
EHEC outbreak in Germany
In Germany, the daily numbers of reported HUS/EHEC cases have steadily decreased since they peaked on 22 May. Nevertheless, the cumulative numbers of cases from Germany continue to rise, primarily owing to delays in notification.Investigations by the German authorities indicate that the vehicle of the bacterium responsible for the outbreak, enteroaggregative verocytotoxin-producing E. coli (EAggEC VTEC) O104:H4, is sprouted beans and sprouted seeds, and the Robert Koch Institute has warned people in Germany not to eat raw sprouts of any origin. In Germany, the latest date of onset of bloody diarrhoea is 22 June for HUS cases and 26 June for EHEC cases. The last known date of illness onset in a patient with confirmed E. coli O104:H4 infection was 18 June 2011.
Global situation of E. coli O104:H4 infections
The table below shows the total number of globally reported (as of 30 June) cases of and deaths from E. coli (EAggEC VTEC) O104:H4 infection since the beginning of the outbreak in Germany on 1 May 2011, now including the cases from the outbreak in the Bordeaux region of France. In total, 16 countries in Europe and North America have reported 4137 cases of E. coli O104:H4 infection, including 50 fatalities.| Country | HUS | EHEC | ||
|---|---|---|---|---|
| Cases | Deaths | Cases | Deaths | |
| Austria | 1 | 0 | 4 | 0 |
| Canada | 0 | 0 | 1 | 0 |
| Czech Republic | 0 | 0 | 1 | 0 |
| Denmark | 9 | 0 | 14 | 0 |
| France | 8 | 0 | 10 | 0 |
| Germany | 845 | 31 | 3154 | 17 |
| Greece | 0 | 0 | 1 | 0 |
| Luxembourg | 1 | 0 | 1 | 0 |
| Netherlands | 4 | 0 | 7 | 0 |
| Norway | 0 | 0 | 1 | 0 |
| Poland | 2 | 0 | 1 | 0 |
| Spain | 1 | 0 | 1 | 0 |
| Sweden | 18 | 1 | 35 | 0 |
| Switzerland | 0 | 0 | 5 | 0 |
| United Kingdom | 3 | 0 | 3 | 0 |
| United States of America | 4 | 1 | 2 | 0 |
| Total | 896 | 33 | 3241 | 17 |
Note
EHEC and HUS have exclusive notification categories, so case numbers should not overlap. The figures in any rapidly evolving outbreak, however, are provisional and subject to change for a variety of reasons.In providing the above information, WHO wishes to recognize the contribution of its Member States, and technical partners such as the European Commission, the European Centre for Disease Prevention and Control and a number of WHO collaborating centres.
Starting from 4 July 2011, WHO/Europe will be issuing these updates as required, and not daily.
